- The Lyon vs Manchester United match will be played on Thursday, 10 April 2025, at 1:00 PM EAT at Groupama Stadium.
- United is still the only team unbeaten in the competition.
- In their last four encounters, Lyon has never defeated United.
Manchester United will be aiming to extend their strong form in the Europa League as they travel to France to face Lyon at Groupama Stadium in the first leg of their quarter-final tie on Thursday night.
United is the only team in the competition that remains unbeaten this season, with six wins and four draws. Their most recent victory was a 5-2 aggregate win over Real Sociedad in the last 16.
However, their domestic form tells a different story. Mired in inconsistency, they languish in 13th place in the Premier League, having accumulated just 38 points from 31 matchess.
Since the appointment of manager Ruben Amorim in November 2024, replacing Rud Vanesroy, their league struggles have persisted.
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Having suffered a 1-0 defeat to Nottingham Forest and been held to a 0-0 draw by Manchester City in the Manchester Derby, United enters this match determined to secure a first-leg win.
They are targeting the Europa League title to salvage a disappointing domestic season while also striving for a spot in next season’s UEFA Champions League.
Meanwhile, Lyon sit fifth in Ligue 1 with 48 points from 28 matches.
They head into this fixture at home buoyed by a 2-1 win over top-four rivals Lille over the weekend.
Highly-rated young midfielder Rayan Cherki scored the winning goal in that match and is one to watch on Thursday night.
His eight assists in this season’s Europa League have already set a joint-record for a player in a single season, matching the tally of former Atlético Madrid player Diego from the 2011/12 campaign.
After a seven-game winless streak in all competitions between mid-January and early February, Lyon have bounced back, winning seven of their last 10 matches, including six of their last seven.
Lyon finished in the top eight in the group stage of the Europa League and triumphed over Romanian side FCSB 7-1 on aggregate in the last 16.
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What time does Lyon vs Manchester United start?
The Lyon vs Manchester United match will kick off at 10:00 PM EAT / 8:00 PM BST at Groupama Stadium on Thursday, April 10, 2025.
Lyon vs Manchester United team news
Lyon have suffered a major blow ahead of this crucial match, as they will be without key attacking players Malick Fofana and Ernest Nuamah, who are sidelined with knee and ACL injuries, respectively, following their last match against Lille.
Jorge Maciel, acting as head coach while Paulo Fonseca serves a nine-month ban for confronting a referee, will likely have to replace Nuamah with Rayan Cherki, with former Arsenal forward Alexander Lacazette and United’s former Nemanja Matic also expected to feature.
United will still be without Lisandro Martínez (knee), Amad Diallo, Ayden Heaven (both ankle), and Jonny Evans.
Matthijs de Ligt missed the derby, and Kobbie Maino, who recently returned to training after a calf injury, will be assessed before the match.
Luke Shaw is available, but Patrick Dorgu is expected to be included in the squad, while Harry Maguire is fit to continue at center-back despite being substituted early in the Manchester Derby.
Possible Starting Line-ups
- Lyon: Maitland-Niles, Perry, Tagliafico, Niakate, Clinton, Matic, Veretout, Cherki, Almada, Mikautadze, Lacazette.
- Manchester United: Onana, Maguire, Mazraoui, Yoro, Dalot, Dorgu, Casemiro, Ugarte, Fernandes, Garnacho, Hojlund.
Olympique Lyon vs Man United Form Guide
| Lyon Last six matches: WWWWLW (All Competitions) Last game played: Lyon 2-1 Lille (05/04, Ligue 1) Current standing: 5th in Ligue 1 | Man United Last six matches: DDWWLD (All Competitions) Last game played: Man United 0-0 Man City (06/04, EPL) Current standing: 13th in EPL |
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Lyon vs Man United Head to Head
In the four encounters between these two clubs, Lyon has never defeated United, with United securing two wins and the other two encounters ending in draws. Their most competitive meeting came in the 2008 Champions League Round of 16, where the first leg ended 1-1 before United triumphed 1-0 in the second leg, advancing with a 2-1 aggregate score.
- Lyon: 0
- Draws: 2
- Man United: 2
Lyon vs Man United Prediction
Although United’s Premier League form has been inconsistent, securing the Europa League title is a key priority for them this season.
Their unbeaten run in the tournament makes them strong contenders for a win in this match.
However, Lyon, buoyed by their recent form, will not be an easy opponent. They will aim to take advantage of their home ground before heading to Old Trafford for the second leg.
Despite both teams having the ability to win, a draw between Lyon vs Manchester United is also a plausible outcome, given the recent scoring and conceding tendencies of both sides.