Liverpool welcome Leicester City to Anfield on Wednesday as both teams prepare to battle it out for a place in the semis.
Liverpool and Chelsea are the only teams to have played all of their scheduled Premier League games as well as playing in Europe and reaching the quarters.
Leicester have been on a 10-day break due to a COVID-19 outbreak, whereas Liverpool are in the midst of a run of four games in 10 days.
The Reds beat Preston North End 2-0 with pretty much their second team in the Round of 16 in October.
Meanwhile, Leicester battled to a 4-2 shootout victory against Brighton after the match ended 2-2 in normal time.
Play here to make your predictions for the mouthwatering clash.
What time does Liverpool vs Leicester start?
The game kicks off 10:45pm Kenyan time at Anfield.
Liverpool vs Leicester team news
Thiago, Fabinho, Virgil Van Dijk and Curtis Jones all tested positive for coronavirus and will sit this one out.
Jordan Henderson and Harvey Elliot are also sidelined, meaning youngster Tyler Morton and James Milner are set to start again.
The front three of Sadio Mane, Diogo Jota and Mohamed Salah is likely to remain unchanged.
For the visitors, Wesley Fofana, Jonny Evans, James Justin and Caglar Soyuncu are all injured.
Kelechi Iheanacho, Ademola Lookman and Ayoze Perez are also unavailable.
Jamie Vardy is likely to get the nod ahead of Patson Daka, supported by James Maddison and Youri Tielemans.
Liverpool vs Leicester head to head
The reds have won 14 times out of the 24 matches played between these two sides, with Leicester winning just 6, including a 3-1 victory last time they met.
Liverpool vs Leicester current form
The hosts are unbeaten in their last five matches, drawing just once and winning all the rest.
Leicester on the other hand have won twice and lost twice in that run, sharing the spoils in one game.
Liverpool vs Leicester prediction
No doubt that this will be a cracker of an encounter filled with goals but Liverpool are poised to come out on top.