- Here is the Real Betis vs Real Madrid prediction for the 2026/27 La Liga match
- The two teams will meet on Friday, September 4, at the Estadio La Cartuja de Sevilla. .
- Kick-off is set for 9:00pm EAT.
Real Madrid will put their unbeaten start in the 2026/27 La Liga season on the line when they visit Real Betis at Estadio La Cartuja de Sevilla on Friday night with the visitors looking to maintain their push for an early lead at the top of the table.
While Madrid have collected maximum points from their opening three matches, Betis have made a mixed start.
Manuel Pellegrini’s side have six points from their first three games, but their heavy defeat to Levante last time out means they will have plenty to prove against one of the league’s early pace-setters.

Betis had every reason to feel confident after beginning the campaign with back-to-back 1-0 victories over Real Sociedad and Valencia. However, their unbeaten start came crashing down in spectacular fashion when they conceded five times against Levante.
The 5-2 defeat exposed defensive problems that Pellegrini will be desperate to address before facing a Madrid attack that has already scored 10 goals in three league matches.
There are, however, reasons for Betis to believe they can make life difficult for the visitors. They have been particularly stubborn when facing Real Madrid on home soil and have avoided defeat in their last four meetings with Los Blancos in front of their own supporters.
Betis also have a reliable scoring record, having found the net in each of their last 11 league matches. That run suggests Madrid cannot afford to become complacent, particularly if the hosts manage to exploit spaces behind the visitors’ defensive line.

Madrid, meanwhile, have wasted little time finding their rhythm under Jose Mourinho. After beginning with a narrow 2-1 victory away to Espanyol, they produced emphatic home wins over Real Sociedad and Malaga.
Their latest outing ended in a 4-0 triumph, with Jude Bellingham once again making his presence felt while Kylian Mbappe continued his impressive scoring record in Spain.
Mourinho’s team now have the opportunity to move three points clear of Barcelona, who do not play until Sunday. That should provide additional motivation, although their recent record in this particular fixture offers Betis some encouragement.
Madrid’s last away victory over Betis came in August 2021, meaning they will have to overcome a ground where they have struggled in recent seasons.
What time does Real Betis vs Real Madrid kick off?
Real Betis vs Real Madrid will take place on Friday, September 4, 2026 at Estadio La Cartuja de Sevilla.
The match is scheduled to kick off at 9:00pm EAT
Real Betis vs Real Madrid team news
Betis will be without Diego Conde, Aitor Ruibal and Giovani Lo Celso, who are all sidelined through injury.
Dani Ceballos is back at the club after completing a free transfer from Real Madrid, but his fitness situation could prevent him from featuring against his former side.
Pellegrini is expected to make alterations following the disappointing performance against Levante. Diego Llorente, Pablo Fornals and Cucho Hernandez are among those pushing for places in the starting XI.
Madrid also have several players unavailable. Raul Asencio, Ferland Mendy, Thiago Pitarch and Rodrygo remain out injured, while Eder Militao is still working his way back from a serious hamstring problem.
Aurelien Tchouameni and Endrick are both nearing a return but face a late fitness test ahead of the trip to Seville.
Mourinho could rotate his team after the comfortable victory over Malaga, with Denzel Dumfries, Ibrahima Konate, Bernardo Silva and Arda Guler all in contention to return to the starting lineup.

Real Betis possible starting lineup
Valles; Bellerin, Llorente, Natan, Garcia; Roca, Fornals; Antony, Isco, Riquelme; Cucho
Real Madrid possible starting lineup
Courtois; Dumfries, Konate, Huijsen, Cucurella; Valverde, Silva; Guler, Bellingham, Vinicius; Mbappe
Real Betis vs Real Madrid head-to-head record
Recent meetings have been surprisingly competitive despite the difference in the clubs’ resources.
Betis have not lost any of their last four home meetings with Madrid, a run that includes a 1-1 draw in April when Hector Bellerin scored a late equaliser.
Madrid’s most recent victory at Betis came back in August 2021, when they secured a 1-0 win.
That record should give the hosts confidence heading into Friday’s contest, although Madrid arrive in considerably better scoring form than they have shown in some of their recent visits to Seville.

Real Betis vs Real Madrid prediction
Betis should not be written off simply because of their defeat to Levante. Their strong record against Madrid at home and consistent ability to score means they could create problems for the visitors.
The concern for Pellegrini, however, is whether his defence can cope with Madrid’s attacking quality. Mbappe, Vinicius Junior, Bellingham and Guler give Mourinho several different avenues through which to hurt the hosts.
Madrid may not have everything their own way, but their greater depth and current momentum should eventually tell.
Betis are likely to make the contest uncomfortable and could find the net, but Madrid’s attacking firepower should prove decisive.
With the chance to temporarily open up a three-point advantage at the summit over Barcelona, Mourinho’s side are expected to leave Seville with another victory and maintain their perfect start to the campaign.
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