- Looking for Barcelona vs Olympiacos prediction? Check match preview, key stats, team news and betting insights.
- The Barcelona vs Olympiacos UEFA Champions League match will be played at the Estadi Olimpic Lluis Companys on Tuesday night.
- Kickoff is at 7.45PM EAT.
Barcelona will be chasing their second win of the UEFA Champions League 2025/26 campaign when they host Greek side Olympiacos on Tuesday night for the Matchweek Three clash at the Estadi Olimpic Lluis Companys.
The Blaugrana began their 30th Champions League campaign with a solid 2-1 victory over Newcastle.
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However, their impressive eight-match unbeaten streak in the league phase was halted by defending champions Paris St Germain, who edged them out with a 2-1 scoreline.
This result left the Catalan giants in 16th position, making a triumphant return at home all the more critical.
Their momentum was further disrupted just before the international break, suffering a stunning 4-1 La Liga defeat to Sevilla.
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This was far from an ideal outcome for Hansi Flick’s squad, who last weekend narrowly escaped a dominant Girona side, snatching a 2-1 victory to mark Flick’s 200th goals in charge.
Despite the recent turbulence, they remain in second place on the domestic table with 22 points, just two behind leaders Real Madrid.

Meanwhile, Olympiacos make a welcome return to the UEFA Champions League since 2021 after clinching the Greek Super League title last season.
However, their comeback has been a baptism of fire, with the team securing only one point from a possible six.
They opened their campaign with a disappointing goalless draw against Pafos, who played with ten men for most of the match.
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Their second outing was a 2-0 defeat at the hands of Arsenal at the Emirates Stadium. In the Greek Super League, they sit second with 16 points, one behind PAOK, who defeated them 2-1 before the international break.
However, Jose Luis Mendilibar’s men returned to winning ways with a 2-0 victory over AEL on Saturday. They will therefore travel to Spain with confidence, seeking their first Champions League win.
Here are the key details for Barcelona vs Olympiacos.
What time does Barcelona vs Olympiacos kick off?
Barcelona vs Olympiacos UEFA Champions League match, is set for Tuesday, October 21, at the Estadi Olimpic Lluis Companys, with kick-off at 7:45 PM EAT.
Barcelona vs Olympiacos team news
The hosts are grappling with a significant injury list. Robert Lewandowski is expected to miss out after sustaining a hamstring injury during the international break.
Joan García (meniscus tear), Pablo Gavi (arthroscopy), and Marc-André ter Stegen (back injury) are also sidelined.
On Monday, all first-team players took part in training except for Andreas Christensen, who missed out due to illness and is a doubt for Tuesday’s squad.

Raphinha and Ferran Torres are still undergoing rehabilitation and are unlikely to feature.
The visitors will be without Rodinei and Gabriel Strefezza due to various injuries. Additionally, Nikos Botis, Remy Cabella, Ruben Vezo, Yusuf Yazici, Gustavo Mancha, and Konstantinos Angelakis are ineligible after being left out of Olympiacos’ league phase squad.
Barcelona vs Olympiacos Probable Line-ups
- Barcelona: Szczesny; Kounde, Araujo, Cubarsi, Martin; De Jong, Garcia, Casado; Yamal, Fermin, Rashford
- Olympiacos: Tzolakis; Costinha, Retsos, Pirola, Ortega; Garcia, Hezze; Martins, Chiquinho, Podence; El Kaabi
Barcelona vs Olympiacos: Head-to-Head and Current Form
These two sides have met only twice in competitive history.
They faced off in the 2017/18 Champions’ League group stage, where Barcelona won the first leg 3-1 before a goalless draw in the reverse fixture.
Head-to-Head Record
- Previous Meetings: 2
- Barcelona Wins: 1
- Draws: 1
- Olympiacos Wins: 0
Current Form (All Competitions)
- Barcelona: W W W L L W
- Olympiacos: D-W-W-L-L-W

Barcelona vs Olympiacos Prediction & Key Betting Facts
Barcelona’s last games against Greek opponents in 2017 extended their unbeaten run to nine matches (W7 D2), including six clean sheets in the last eight.
The Catalan club have lost only two of their 14 matches against Greek teams, winning ten.
They have a perfect record in all seven home games versus Greek visitors, scoring 29 goals and conceding just four.

Olympiacos have won only one of their last 12 matches against Spanish sides (D3 L8) and have failed to score in four of the last five.
The Greek club have never won in Spain, losing 14 of their 16 visits and conceding 38 goals.
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Furthermore, they have won only two of their last 22 Champions’ League group stage/league phase games (D3 L17) and are on an 11-match away losing streak in the competition.
That said, Barcelona enters this match as the clear favorite to secure all three points.
However, given their struggles in the previous two league phase matches, they cannot afford to underestimate an Olympiacos side capable of springing a surprise.
Therefore, this is a match that promises plenty of fireworks for the full 90 minutes.
