For a place in the fifth round of the League Cup, Tottenham Hotspur have to ignore fatigue from the fixture pile-up and brave the blue storm Chelsea bring with them.
Mourinho will go up against a familiar face in Lampard, bearing in mind that this is their second of three games in just a five-day period.
Both sides come into the Tuesday night fixture in desperate need for a win, after both only managing draws over the Premier League weekend.
Spurs were held to a 1-1 draw by Newcastle, while Chelsea had to pull off a great second half performance to fight back from a 3-0 deficit to snatch a draw at West Bromwich Albion.
What time does Spurs vs Chelsea start?
The game kicks off at 10 pm Kenyan time at the Tottenham Hotspur Stadium.
Spurs vs Chelsea team news
The visitors suffered the cost of individual errors over the weekend and that reshuffle could see new signing Ben Chilwell make his full debut, as well as latest signing Edouard Mendy between the sticks.
Callum Hudson-Odoi, who scored over the weekend, will be expecting to start alongside Olivier Giroud and possibly Tammy Abraham.
Heung-Min Son has been ruled out due to a hamstring injury and joins Japhet Tanganga and returning star Gareth Bale on the sidelines.
Another new addition to the squad, Sergio Reguilon could make his debut at left-back with Steven Bergwijn expected to start as well.
Spurs vs Chelsea head to head
Chelsea have a superior record against their hosts- winning 30 out of the 53 matches played so far.
Spurs have won 10 and another 13 have ended in draws.
In the last five matches, Chelsea have been victorious on three occasions with Tottenham winning the remaining two.
Spurs vs Chelsea current form
There is nothing separating these two sides in terms of form. Both have won once, lost another and drawn a game.
Spurs vs Chelsea prediction
This will be one hard match to call, though a goal for either side is the most likely outcome.
Despite Tottenham having home advantage, Chelsea have more depth and experience in the squad that could help them edge their hosts, especially if it goes past the 90.